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In hypertension, GLP-1 attenuates the excitability of carotid body cells diminishing sympathetic activation, augments renal blood flow to promote natriuresis and diuresis as well as facilitates generation of nitric oxide in vascular smooth muscle cells

Moreover, Indian pharmaceutical giants such as DRL, Sun Pharma, Biocon, and Cipla are already developing their own versions of GLP-1 receptor agonists, including generic variants of Semaglutide

Meanwhile, it was demonstrated that obesity was significantly associated with the increased risks of numerous complications, including cardiovascular disorders, diabetes mellitus, and certain cancers [2,3,4,5]

Christensen, M., Vedtofte, L., Holst, J

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These examples underscore the potential for GLP-1 RAs to address a wider range of health challenges in the future
