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Weekly weighing helps catch small regains before they become large ones

The slow titration from 2.5 mg upward exists for a reason

Sensitivity Analyses Modified ITT analyses resulted in fewer patients achieving weight loss thresholds, smaller weight reductions, and slightly attenuated comparative effect estimates, though tirzepatide remained associated with significantly greater weight loss in all analyses (eResults 2.1, eFigure 3, eFigure 4, eFigure 5, and eFigure 6 in Supplement 2)

Semaglutide is a single GLP-1 receptor agonist

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Methylphenidate (Ritalin) and atomoxetine (Strattera), have been studied for use during breastfeeding with limited negative effects reported on the infant