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Steps of the carnitine shuttle system Formation of Acyl-Carnitine: Long-chain fatty acids in the cytosol are activated to acyl-CoA, which then reacts with carnitine in the presence of CPT I to form acyl-carnitine

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Why Was the Study Undertaken

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What is meant by the term membrane asymmetry and how is this feature created and maintained

In this way, carnitine protects the cell from the membrane-destabilizing effects of toxic acyl groups, as well as their restraining effects on several enzymes that participate in intermediary metabolism and energy production in the mitochondria