glp-1 how does it work and the kidney: from physiology to pharmacology and outcomes in diabetes What is GLP-1 and how

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Research examining human cardiac samples has revealed several key findings: GLP-1R mRNA transcripts have been consistently detected in all four cardiac chambers from human hearts, at levels approximating those in human pancreas [1] Receptor expression is notably absent in cardiac fibroblasts, coronary artery endothelial cells, and vascular smooth muscle cells according to some studies [1] Human GLP-1R expression appears predominantly in cardiomyocytes, albeit at relatively low levels [2] Interestingly, species differences exist in GLP-1R distribution patterns

10.1016/j.neurobiolaging.2012.04.009 48 HansenG.JelsingJ.VrangN

Many people regain weight when they stop treatment abruptly without a maintenance plan