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The single nucleotide polymorphism rs5400 in SLC2A2 in human CD8 + T cells reduces glucose uptake and inhibits CD8 + T cell proliferation [98]
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Thioredoxin (Trx), present in the cytosol as Trx1 and in mitochondria as Trx2, is oxidized and upregulated in response to oxidative stress and elevated ROS levels
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Trigonelline inhibits Nrf2 via EGFR signalling pathway and augments efficacy of cisplatin and etoposide in NSCLC cells
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