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Description
The team confirmed that 1) CBS protein and H2S levels were elevated in DS cells, 2) that mitochondrial metabolism is impaired in these cells, and 3) demonstrated that CBS inhibition or downregulation improves bioenergetic functions, restores mitochondrial Complex IV activity and consequently improve viability and proliferation rate in DS cells (Panagaki et al 2019)
Boiled water
The Dawed study is one of the first large-scale datasets
2021;131:e143691
2019 May 15;150:145-152
Once reconstituted , adding more water to change the concentration is technically possible but not recommended
