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Tesamorelins effects depend on intact pituitary function and normal GH responsiveness, while AOD9604 works directly on adipose tissue regardless of GH status
Indeed, posttranslational modification of IGFBP3 (e.g., glycosylation, phosphorylation) is an essential determinant of IGF-1s ability to bind the IGF-1R
Weidner, N., Semple, J
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