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43 Pathological cardiac hypertrophy is commonly associated with diverse etiologies such as hypertension, arterial stenosis, myocardial infarction, and dilated cardiomyopathy, which progressively leads to cardiac remodeling and heart failure

After that, they switch to monthly shots

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You can also have a BMI of at least 27 if you also have a weight-related health condition, such as high blood pressure, cardiovascular disease, or obstructive sleep apnoea