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10.3389/FCVM.2022.938567 107

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Firth J., Solmi M., Wootton R.E., Vancampfort D., Schuch F.B., Hoare E., Gilbody S., Torous J., Teasdale S.B., Jackson S.E., et al

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FDX1 is a small protein from the ferredoxin family and contains an Fe-S cluster ( 2+ and release Cu + into the mitochondrial matrix ( + can directly bind to Fe-S clusters, which in turn disrupt their synthesis and function ( Figure 3 ) ( Figure 3 4 Abnormal copper metabolism and liver disease The liver plays a central role in copper metabolism, including absorption, storage, transportation and excretion