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99 A placebo-controlled trial with 45 participants found 600 IU of dl-alpha-tocopherol (equivalent to about 300 IU of active d-alpha-tocopherol) per day and 40 mcg (1,600 IU) of vitamin D3 per day each reduced eczema symptoms more than placebo, but treatment with both vitamin E and vitamin D had an even greater positive effect

Proc Natl Acad Sci USA 96:1038510390 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhang W, Neer EJ

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To my knowledge, no cases have ever been published in a referred journal that document that these therapies cure or even result in significant improvement in cats with hyperthyroidism

Zinc promotes the thyroid hormone, which, in turn, promotes the better absorption of zinc

Conversely, there is no evidence for accumulation of valproyl-CoA in brain tissue, suggesting that the effects of VPA in the CNS are independent of the formation of this metabolite [80]