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A combination of assays, including CSF -syn and other biochemical indicators, MRI imaging markers, SPECT or PET imaging, non-motor symptoms, and cognitive function scores, should be utilized to detect early PD because individual biomarkers are difficult to diagnose reliably

10.1167/iovs.14-15025 Invest Ophthalmol Vis Sci

all point out an increase in plasma enzymatic activity in more than 50% of patients after the dietary intervention, although no explanatory hypothesis has been yet suggested [83,85,86,123]

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