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D.TownsendD
Furthermore, NRF2 enhances drug resistance by inducing the expression of ATP-binding cassette (ABC) transporters such as ABC sub-family C member 1 (ABCC1) and ABC sub-family G member 2 (ABCG2), which efflux chemotherapeutic agents out of cells
doi:10.4103/abr.abr_157_17 62 Nemati, M., Nemati, S., Taheri, A.-M
This has contributed to addressing the question of missing heritabilitywhile rare pathogenic variants explain a portion of a trait, adding the modest impact of common variants helps account for the unexplained heritability observed in many conditions
doi: 10.1038/nature08302
Robb, G
