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Incubations where the total parent amide decreased below 80% of the t 0 baseline sample or the amine metabolite was detected were determined to be hydrolysed
They exert their activities through increasing the expression of TJ proteins, reducing intestinal inflammation, and modulating the local immune responses [118]
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Of the 48 inter-molecular NOE restraints, only 2 NOEs could be assigned unambiguously and correspond to contacts between p53-Trp53 HE# - FOXO4-Leu160 HD# and p53-Trp53 HD#FOXO4-Leu109 HD# (Supplementary Note 1)
Splitting the total across two injections is common in higher-dose reference schedules
