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Nutrients 15 , 2749 (2023)

L-Carnitine supports fat metabolism and energy production

These fatty acids are thought to be the main energy sources used during low- to moderate intensity exercise.2 Types of L-carnitine and Their Uses The two main variations of L-carnitine that are supplemented in the diet are L-carnitine tartrate and acetyl L-carnitine

Acetyl-L-carnitine may also function as a histone deacetylase inhibitor, promoting transcription of genes involved in mitochondrial biogenesis and cellular stress resistance

While transient anorectic effects likely contribute to initial weight loss, the sustained reduction in adiposity and the unchanged food intake observed during chronic treatment indicate a dominant role for peripheral energy expenditure

This also explains why, to a certain extent, DNA damage prevents telomerase from continuing to function