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This dysregulation leads to energy depletion and triggers hepatocyte pyroptosis [176]

P.de VosW

Expert Opin Biol Ther 8:19551962

The mechanism through which SDH contributes in development of oxidative stress may be related to that the activation of SDH produces excess of NADH which, in turn, leads to more glucose being channeled through the polyol pathway and enhanced NADH oxidase which generates excess of ROS and thus oxidative stress [69,73]

Falling threshold for treatment of borderline elevated thyrotropin levelsbalancing benefits and risks: evidence from a large community-based study

SIRT2 expression is enhanced in granulosa cells of EMS patients, indicating that EMS impacts GCs metabolic pathways, which may be mediated by SIRT2 (96)
