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It catalyzes the addition of glycine to -glutamylcysteine created by GCL to form GSH, -L-glutamyl-L-cysteinyl-glycine, a reaction again driven by the hydrolysis of ATP

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The expression of genes involved in the stress response (down-regulation of heat shock protein 70, hsp70 ), antioxidant defence (down-regulation of sod1, accompanied by up-regulation of sod2 ), and DNA repair (up-regulation of 8-oxoguanine DNA glycosylase) was significantly perturbed

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They also strengthen hair follicles and increase blood flow to the scalp to boost hair growth