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The link between ER stress, ethanol metabolism, and apoptosis highlights the multifaceted nature of the cellular response to chronic alcohol exposure

Yusupov, M

The evolution of GSH in aging fibroblasts showed a sudden increase in its concentration just before cell death, whereas GPx activity was already decreasing at the beginning of passages, and that of glutathione reductase was constant and reaching a very low level at the end of the cell culture, suggesting that the GSH system was probably involved in cell degeneration associated with aging [18]

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Among the 4 cancer cell lines, K1 cells exhibited higher GPX4 gene expression relative to MDA-T32, MDA-T68, and TPC-1 cancer cells and control HThF