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Yes, although Vitamin B12 is generally safe, some peopleespecially when taking high doses or injectionsreport side effects like anxiety, insomnia, acne, or palpitations

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The most comfortable way of doing this is by measuring the methylmalonic acid (MMA) in the urine, which determines how much vitamin B12 the cells actually receive

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This leads to higher concentrations of these feel-good peptides, potentially contributing to both the calming effects and the mild analgesic properties some users report

Vaginal estrogen and DHEA To treat vaginal dryness, irritation, or pain during sex, local vaginal estrogenavailable as a cream, tablet, or ringdelivers a small amount of estrogen directly to vaginal tissue