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CRISPR/Cas9 To generate CRISPR/Cas9 mutants, sgRNAs were designed using the Cas-Designer and Cas-OFFinder at for a SpCas9 protospacer adjacent motif (PAM) sequence and with a length of 19 bp (without PAM) against the Arabidopsis thaliana (TAIR10) genome (Bae et al ., 2014

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Lau et al., Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimers disease transgenic mouse model, Sci

If possible, randomized controlled trials should evaluate whether providing neonates with circadian- as well as stage-of-lactation-matched expressed milk improves clinical outcomes

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Currently, the application of FMT in oncology lacks unified criteria for donor selection, standardized protocols for fecal material preparation, and consensus on administration routes and dosages (125)