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Phentermine cannot fully overcome the biology of chronic sleep deprivation, so patients running consistently short on sleep will find weight loss harder regardless of medication
10.1016/j.bbagen.2012.09.008 118 LushchakV
Standardizing formulations of SFN and ensuring consistent bioavailability are also critical for safety and efficacy
RodriguesDMFreitasACRocha-SantosTAVasconcelosMWRorizMRodrguez-AlcalLMet al
Studies document effects on 31.2% of human genes (approximately 4,000+ genes) with 50% expression change, suppressing RNA production in 70% of 54 genes overexpressed in metastatic colon cancer
AACR, 2012
