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Hardin et al., 1990), TIM (Sehgal et al., 1994), CRY (Emery et al., 1998

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It helps protect cells from damage caused by free radicals, preventing premature aging

found that the ferroptosis-related gene ALOX15 was significantly upregulated in neurons of STZ-induced T1DM mice and HG-treated SH-SY5Y cells, promoting the development of diabetic peripheral neuropathic pain by enhancing neuronal ferroptosis [159]