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Incoming stress signals to the PVN of the hypothalamus through a wide range of humoral and neural pathways are caused by different factors including infections, pain, emotional distress, and cardiovascular changes due to physical activity [3]

-Black Hairy tongue Black hairy tongue is a painless, benign disorder caused by defective desquamation and reactive hypertrophy of the filiform papillae of the tongue (18)

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L-carnitine increases mitochondrial energy metabolism and plays a specific role in minimizing myocardial ischemia and replacing the depleted carnitine, which can occur during the metabolic stress of an acute myocardial infarction