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Research Findings The research history of AOD9604 spans multiple phases of preclinical and clinical development, with generally positive findings regarding efficacy for body fat reduction and favorable safety compared to growth hormone, though ultimate regulatory approval has remained elusive

Semi-saturation mutagenesis on the conformationally flexible H241 residue shows that only H241N and H241Q retained low activity, indicating that H241 is vital for the conformation required to bind PLP and tyrosine

May-Jun 2013;23(3):143-7
M.TigyiG.et al (2010)

[Google Scholar] 30.Lawson L.D., Wang Z.J
