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In addition, CoQ10 has been observed to significantly decrease the levels of oocyte apoptosis, double-strand breaks, and DNA damage ( In addition, research has found that high levels of CoQ10 in the follicular fluid were associated with improved embryo morphokinetic parameters and higher pregnancy rates ( in vitro maturation rate of immature oocytes in patients with endometriosis compared to those who do not receive the supplement (Romero et al., 2020)

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These signalling pathways are activated by the binding of different ligands to their specific melanocyte cell surface receptors (Figure 3)