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Yamaguchi, J

doi: 10.1016/j.foodchem.2005.05.080

FHRRIKA (Phe-His-Arg-Arg-Ile-Lys-Ala) is a cell-binding and putative heparin-binding domain of bone sialoprotein

doi: 10.1016/j.jdermsci.2023.04.006

The experimental data showed that its active components selectively induced apoptosis in bone-metastatic breast cancer cells while maintaining normal bone tissue activity, indicating its potential value as a targeted therapeutic agent for bone metastasis

It works by promoting the production of brain-derived neurotrophic factor (BDNF), which supports brain health and neuroplasticity
