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This model showed high accuracy in estimating the presence of TLS in the kidney, and the receiver operating characteristic curve revealed a high area under the curve value of 0.92 (Figure 6I)

Recently, all-trans retinoic acid (ATRA), was shown to induce the expression of GS selectively (no effect on GCLC or GCLM) and GSH levels in myeloid-derived suppressor cells [141]

It remains essential to discuss any certified product with the oncology team before use

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Irinotecan can be activated by carboxylesterase 1/2 (CES1/2) and catalyzed to a more active metabolite SN-38, both of which could form an inhibitory complex with TOP1 and DNA (Takano and Sugiyama, 2017)