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However, prolonged or intense physical activity can deplete intracellular GSH levels because GSH is oxidized to its disulfide form, glutathione disulfide (GSSG), during ROS detoxification [69,70]

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Complete knockdown of -catenin barely affected the expression of SNAIL and SLUG in both cell lines, whereas complete loss of ZEB1 with decrease of TWIST1 expression and complete loss of ZEB1 with increase of TWIST1 expression were observed in HCT116-P and HCT116-MT cells, respectively

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