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glutathione peroxidase and gsh levels depletion induces ferroptosis, autophagy, premature cell senescence in retinal pigment epithelial cells GSSG Application
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Aging Cell 19 , e13254 (2020)

Overexpression of SIRT1 or SIRT6 is protective in many disease models in mice, including cancer, type 2 diabetes and cardiovascular disease [11, 47, 106, 131, 184] and leads to a delay in ageing and extension of lifespan [145]

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

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[DOI] [PubMed] [Google Scholar] [109].Kiefer RT, Rohr P, Ploppa A, Dieterich HJ, Grothusen J, Koffler S, Altemeyer KH, Unertl K, Schwartzman RJ, Efficacy of ketamine in anesthetic dosage for the treatment of refractory complex regional pain syndrome: an open-label phase II study, Pain Med 9(8) (2008) 1173201

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