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[DOI] [PubMed] [Google Scholar] 387.Xiao M., Wang T., Zhu T., Wen F

The expression of AANAT, the rate-limiting enzyme for melatonin synthesis, increases in the uterus during early pregnancy, and MT2 receptors are specifically expressed in uterine luminal epithelial cells and uterine glands on the second day of pregnancy (86)

Increased PADI4 expression in blood and tissues of patients with malignant tumors

Glutathione also plays an important role in the detoxification process via its use as a cofactor

This normalization allows for direct comparison of relative changes in organic acids levels over timeand their percentage is independent of their absolute concentrations

Since glutathione metabolism is critical for normal stem cell function and CSCs from breast, liver and gastric cancer show increased glutathione content, we hypothesized that pancreatic CSCs also rely on this pathway for ROS detoxification