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Pharmacokinetics and effects on cyst(e)ine in plasma and urine

eLife 2014

The study involved 411 adult patients with T2DM and was designed as a randomized, double-blind, placebo-controlled trial where patients received varying doses of danuglipron or a placebo

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Owing to the limited availability of specific chemical modulators for many of these channels, we conducted a small-scale pharmacological screen to identify the channels responsible for the impaired Ca 2+ signaling in XKR8 KO cells during NET formation (Fig

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