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(2009) reported a 2.8 point change, which did not reach the MCID threshold and was therefore unlikely to reflect a meaningful benefit in motor symptoms for patients

These benefits were seen within 4 weeks and maintained throughout the 8-week 1,2 In general, combination therapy is more effective than monotherapy in melasma patients

suis GGT-treated epithelial cells can stimulate the formation of pro-oxidative GSH degradation products and extracellular oxygen radicals, leading to necrosis of damaged cells 15
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"Epithalamin and Epitalon in aging and circadian rhythm regulation." Biogerontology , 20(3), 231242
