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[8] Steele ML, Fuller S, Maczurek AE, Kersaitis C, Ooi L, Mnch G

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Additionally, M1 polarization has been associated with the induction of a pentose phosphate pathway, which provides NADPH for the production of reactive oxygen species (ROS) and attenuates mitochondrial respiratory change, resulting in increased ROS production

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Furthermore, the free aniline group could form a hydrogen bond with the catalytic E465 residue of IRAP
