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Contraindications include active infection at the injection site, severe thrombocytopenia, or anticoagulation therapy requiring provider clearance

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Other conditions that make Vitamin B12 absorption more difficult are: Weight loss surgery or another operation that removed part of your stomach Heavy drinking Taking acid-reducing medication for a long time Certain health issues may also lead to the development of vitamin B12 deficiency such as atrophic gastritis, pernicious anemia, Crohns disease, celiac disease, immune system disorders, Graves disease and lupus

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These findings establish the mechanistic basis for the compound and provide proof of concept for its metabolic effects