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The GSSG thus generated is converted back to GSH, either by de novo synthesis or enzymatically by GR

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Notably, competence could only be obtained after addition of glycerol to the culture medium

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1 When IGF-1 binds to IGF-1R, the tyrosine kinase activates the phosphoinositide 3-kinase (PI3K)-AKT pathway and many integral proteins involved in cellular metabolism, apoptosis, cell adhesion, and angiogenesis are regulated within this pathway

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