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Futile cycling A process of using energy in two opposing metabolic pathways without a net effect

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Remember that at this time the active ingredient in the raw liver (cobalamin) was as yet unknown

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The missing piece is often hiding in plain sight, and it moves at a pace that feels almost too easy to count

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Lyophilised vials are stable at 28C until reconstitution

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Diets lacking in vitamin B12 and folate - in particular vegan diets and those low in fresh fruit and vegetables are at risk of vitamin B12 and folate deficiency

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Associated toxicity includes potential headaches and bleeding problems

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