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Supplementary material The Supplementary Material for this article can be found online at: References 1 Adamus-BiaekW.LechowiczL.Kubiak-SzeligowskaA

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Overall, despite the reputation of CoQ as an antioxidant, its action as a prooxidant is actually better documented

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Although there is a lack of specialized research on the direct impact of TMAO on IBD through the PERK pathway, considering TMAOs ERS inducing ability and the critical role of the PERK pathway in IBD, the relationship between the two deserves further in-depth investigation