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In cells that do not express the MR the function of the HSD11B2 enzyme is to protect those cells from the growth-inhibiting effects of cortisone

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[PubMed] [Google Scholar] 90.Shug AL, Shrago E, Bittar N, Folts JD, Koke JR

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To be absorbed, a drug given orally must survive encounters with low pH and numerous gastrointestinal (GI) secretions, including potentially degrading enzymes

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