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To explore whether targeted intervention of Chac2 in neutrophils could alleviate the inflammatory comorbidity of periodontitis, we constructed AAV9 viruses targeting neutrophils to specifically knock down Chac2 (AAV-shCHAC2) and a control virus with no payload (AAV-NC), and administered them via intraosseous injection into a mouse model with periodontitis and diabetes comorbidity

New Phytol 199:650662

SCFAs modulate epithelial cytokine productionincluding IL-6 and IL-8through TLR and NF-B signaling pathways, thereby exerting broad anti-inflammatory functions

(Okra) Abelmoschus esculentus L

Detection of fillings, crowns, bridges, posts, and implants

G.KblerA.GrondonaP.SchmidV.et al (2015)