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This deficiency can be caused by a number of factors, including: An autoimmune disorder that affects the stomach's ability to produce intrinsic factor A genetic flaw that interferes with the body's ability to transport vitamin B12 from the intestine to the bloodstream A low-vitamin B12 diet, like a vegetarian or vegan one Gastrointestinal surgery that involves the removal of a portion of the small intestine or stomach Certain medications that interfere with the absorption of vitamin B12 How does pernicious anemia affect my body

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Abbreviations MetS: Metabolic syndrome IGF-1: Insulin-like growth factor CVD: Cardiovascular disease T2D: Type 2 diabetes RAS: Protooncogene protein P21 NAFLD: Non-alcoholic fatty liver disease OSA: Obstructive sleep apnea HDL: High density lipoprotein TG: Triglyceride PI3K: Phosphatidylinositol-4,5-bisphosphate 3-kinase AKT: Protein kinase B GLUT: Glucose transporter FA: Fatty acid FFA: Free fatty ACID IGF-1R: IGF-1 receptor IGFBP: Insulin-like growth factor binding protein IRS: Insulin receptor substrate KO: Knock out LDL: Low density lipoprotein VLDL: Very low density lipoprotein GH: Growth hormone HOMA: Homeostasis model assessment ROS: Reactive oxygen species References Executive Summary of The Third Report of The

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Comment: Commenters opposed the inclusion of lymphedema compression treatment items in the DMEPOS competitive bidding program due to concerns that competitive bidding could result in reduced access to these items for beneficiaries

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