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2 The main sources of cellular ROS are mitochondria and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, and peroxisomes containing xanthine oxidase and the inducible form of nitric oxide synthase, which produce superoxide anion and nitric oxide, respectively

(PubMed) Sperduto RD, Hu TS, Milton RC, et al

(2020) 15:e0219633

Protein gelation can be triggered by changes in pH, pressure, salt, shearing, the presence of certain solvents, and heat treatment

Another strategy involved the use of SIRT activator SRT1720 and the PARP inhibitor Olaparib, which enhanced SIRT1 activity and increased NAD + 111

Early reduction of glucose uptake after cisplatin treatment is a marker of cisplatin sensitivity in ovarian cancer