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doi: 10.1016/j.ctcp.2010.09.002 87 NyekoR.TumwesigyeN

109 It is important to note that long-term, high-dosage use of licorice can cause sodium and water retention as well as potassium loss that may lead to increased blood pressure and edema

It may also interact with nitric oxide pathways that affect blood vessels and inflammation

Data were normalized to Tbp and analyzed using the Ct method as previously described 136