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(2021) found that increased ROS can affect intestinal cell outcomes and functions by altering the covalent states of NO, leading to further dysregulation

PGRN-boosting therapies There are currently no approved therapies for FTLD- GRN and CLN11

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Originally, the Schilling test was used for this purpose, but it is no longer used in view of the safety factors related to the use of radioactive B12 ( 57 Cocyanocobalamin) (Sobczynska-Malefora et al., 2021)