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GLP-1 medications can provide major health benefits, but recent studies have raised questions about a possible link with NAION, a rare optic nerve condition that can cause sudden vision loss

But despite these encouraging data, retatrutide has not yet received regulatory approval and is not an approved prescription medicine

Published in eClinicalMedicine, the narrative review brings together evidence from dozens of studies to assess how these medications are being used, where they show promise and what concerns remain

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Our objectives were to compare incretin concentrations and rates of glucose production and gluconeogenesis in youth with type 2 diabetes before and after short-term metformin therapy compared with peers with normal glucose tolerance (NGT)