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others with deeper pigmentation or higher oxidative stress may require more sessions

Biochem J (1981) 199(2):3938

(ii) Developing orthotopic tumor-bearing animal models is particularly challenging due to the technical complexity of tumor transplantation surgery, the need for intensive post-operative care, the highly heterogeneous tumor microenvironment (TME) of pancreatic cancer, and the inherent variability in tumor growth and experimental timelines (Stribbling et al., 2024)
[DOI] [PubMed] [Google Scholar] 383.Vecht CJ, Haaxma-Reiche H, Noordijk EM, Padberg GW, Voormolen JH, et al

Pharmacol Rev 47:271330 Cooper AJL (1998) Role of astrocytes in maintaining cerebral glutathione homeostasis and in protecting the brain against xenobiotics and oxidative stress

While cuproptosis and ferroptosis are currently understood to operate through distinct mechanisms, future research may uncover synergistic effects between them
