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Nat Rev Cancer 2011;11:761-74

We further investigated relevant publications over the past two decades by searching the PubMed, Web of Science, and Google Scholar databases using keywords related to physical exercise, PD, ferroptosis, and neurotrophic factor antioxidant signaling

Kindlon T
S., Previll L

NF-B, nuclear factor-kappa B

These alterations weaken the bloodbrain barrier, allowing systemic inflammatory mediators already elevated in COPD, particularly IL-1, IL-6, CRP, and TNF-, to enter the CNS and perpetuate glial activation [33, 55]
