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Acetyl-L-Carnitine is the acetylated form of carnitine structurally modified to cross the blood-brain barrier with high efficiency, giving it a cognitive and nootropic dimension that standard L-Carnitine does not possess

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Urinary loss is thereby minimized, although excess amounts can be eliminated when necessary

Nevertheless, the different levels of carnitine dehydratase and carnitine racemase activities explain why the highest productivities are achieved with crotonobetaine [63]