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Juni 2021 08:19 - John Michael M

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To clarify these observations, here, we report a functional decline of GABA INs in the SM cortex of SMA mice assessed by reduction in the number and signalling of GABAergic neurons, changes in the expression and distribution of the GABA-synthesizing enzymes (GAD) and its precursor, Gln, as well as alterations in the density and morphology of PV+ INs

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While all these neuropeptide system have been implicated in motivational effects of alcohol, their role in mediating withdrawal symptoms as well as excessive alcohol consumption associated with dependence remains to be determined