mercury glutathione synthesis in cytosol and compartimentalization in Glutathione-related genetic polymorphisms are associated

ROS, such as superoxide (O 2 - ), can be produced in mitochondrial complexes I and III in components of the tricarboxylic-acid cycle, including -ketoglutarate dehydrogenase (EC 1.2.4.2), and in the outter mitochondrial membrane, damaging cell components such as lipids, proteins and DNA [25, 47]

J Am Chem Soc 127:812813 Chen Y, Montana DM, Wei H, Cordero JM, Schneider M, Guvel XL, Chen O, Bruns OT, Bawendi MG (2017) Shortwave infrared in vivo imaging with gold Nanoclusters

N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease

Integration of AI, particularly through combined learning with multi-omics, spatial omics, histopathological imaging, and other multimodal data, may further improve the accuracy and generalizability of system modeling

Overexpression of NOX4 leads to increased ROS generation and may induce endothelial cell death or apoptosis

At 6 and 12 months of age comparing WT and BACHD mice, our findings did not show remarkable differences between pro and anti-inflammatory cytokines in central and periphery tissues analyzed (Supplementary data, figures S47 and figures S1013)