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Activated PARP-1 cleaves NAD+ into nicotinamide and ADPribose and polymerizes the latter on nuclear acceptor proteins

A new compound reduced hippocampal inflammation and improved memory in Alzheimers model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and reverse memory deficits in rats with induced Alzheimers disease

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DHA@MIL-101 NRs self-disassembled in the acid microenvironment to dissociate Fe 3+ , achieving GSH consumption-mediated redox reaction and Fe 2+ -mediated Fenton reaction (Figure 5D)