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[DOI] [PubMed] [Google Scholar] 384.Kang, P

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Animals A total of 30 adult male Wistar rats (average weight of 140150 g b.wt.) were obtained from the lab animal facility in Helwan, Egypt, for this investigation

Conversely, as both drugs are vasodilators, a certain degree of caution has been observed for combination therapy with PDE5Is and alpha-blockers due to the potential cumulative effects on blood pressure described in some studies [394,405,426]